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Eight weeks of omeprazole 20 mg significantly reduces both laryngopharyngeal reflux and comorbid chronic rhinosinusitis signs and symptoms: Randomised, double-blind, placebo-controlled trial. Gastroesophageal reflux recommended treatment dose and duration with proton-pump inhibitor PPI compared to placebo significantly reduces the signs and symptoms of laryngopharyngeal reflux LPR and comorbid chronic rhinosinusitis CRS. Double-blind randomised placebo-controlled trial. Eight weeks of treatment with omeprazole 20 mg once daily OD.

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